J. C. Stachowiak

This study shows that liquid-like condensates containing both actin branching and bundling proteins can modulate the competition between these processes, leading to organized actin structures similar to those in migrating cells.

This paper develops a transferable model to predict biophysical properties of IDPs, showing agreement with experimental data on size, conformation, and SAXS profiles.

This study shows that protein phase separation on both sides of a lipid bilayer is coupled through an entropic mechanism driven by lipid compression.

This study measures steric pressure generated by intrinsically disordered domains of AP180 at membrane surfaces, finding that they produce significant pressure through entropic and electrostatic mechanisms, independent of molecular weight.

This study shows VASP forms liquid-like droplets that drive actin polymerization and bundling by creating actin-rich rings that transition into linear bundles.

This paper investigates how liquid-like protein assemblies on membranes drive membrane bending by creating compressive stress, leading to the formation of membrane tubules.

This study investigates how syndecan-1 mechanical tension responds to substrate stiffness and fluidic shear stress in endothelial cells.

The paper shows that weak, liquid-like interactions between Eps15 and Fcho1 enable efficient endocytosis by promoting dynamic protein assembly and preventing stalling of vesicle budding.

The paper shows that BAR domain-containing proteins drive membrane fission by crowding disordered domains, challenging the idea that BAR scaffolds stabilize membranes.