Author

K. Heiser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:imaging· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. Agrawal· 1 shared A. E. Carpenter· 1 shared A. S. Low· 1 shared B. A. Earnshaw· 1 shared B. Fogelson· 1 shared B. L. Probst· 1 shared B. M. Mendivil· 1 shared B. Mostofian· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Agrawal

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Author profile →

2 papers

Recent·Most cited

Functional immune mapping with deep-learning enabled phenomics applied to immunomodulatory and COVID-19 drug discovery

M. F. Cuccarese, B. A. Earnshaw, K. Heiser, B. Fogelson, C. T. Davis, P. F. McLean, H. B. Gordon, K.-R. Skelly, F. L. Weathersby, V. Rodic, I. K. Quigley, E. D. Pastuzyn, B. M. Mendivil, N. H. Lazar, C. A. Brooks, , C. C. Gibson

This paper develops a deep-learning enabled phenomics platform to identify immune-modulating compounds and applies it to study SARS-CoV-2 infection and cytokine storm, identifying clinically relevant compounds and new drug candidates.

bioRxiv · Aug 2, 2020 · PreprintImmunology

HER2 Cancer Protrusion Growth Signaling Regulated by Unhindered, Localized Filopodial Dynamics

W. Y. Lam, Y. Wang, B. Mostofian, D. Jorgens, S. Kwon, K. Chin, M. Carpenter, T. Jacob, K. Heiser, A. Agrawal, J. Wang, X. Nan, Y. H. Chang, D. M. Zuckerman, J. Gray, , T. Q. Vu

This study investigates how HER2 dynamics in filopodia regulate protrusion growth and signaling in breast cancer cells, revealing distinct motion patterns and functional roles in protrusion-based signaling.

bioRxiv · Jun 2, 2019 · PreprintCancer Biology