ImmunologybioRxiv
Negative feedback by NUR77/Nr4a1 restrains B cell clonal dominance during early T-dependent immune responses
J. F. Brooks, C. Tan, J. L. Mueller…·J. Zikherman
This study shows that NUR77/Nr4a1 negatively regulates B cell clonal dominance in early T-dependent immune responses to maintain diversity in the germinal center niche.
DOI 10.1016/j.celrep.2021.109645