BiochemistrybioRxiv
Structures of PKA-phospholamban complexes reveal a mechanism of familial dilated cardiomyopathy
J. Qin, J. Zhang, L. Lin…·Z. Yuchi
This study reveals how PLN mutations reduce phosphorylation by altering conformation and PKA interactions, contributing to DCM.
DOI 10.7554/elife.75346