Cancer BiologybioRxivPreprint
Androgen blockade primes NLRP3 in macrophages to induce tumor phagocytosis
K. K. Chaudagar, R. Srikrishnan, S. Mei…·A. Patnaik
This study shows that androgen blockade increases NLRP3 in macrophages, which when combined with NLRP3 agonist, enhances cancer cell phagocytosis and tumor control in a mouse model of prostate cancer.
DOI 10.1101/2023.09.15.557996