K. Kierdorf

This study identifies DNA damage signaling in Drosophila macrophages as a key regulator of cytokine release and oxidative stress response through JNK and unpaired-3.

This study shows that intestinal macrophages refine the enteric nervous system early in life by pruning synapses and phagocytosing neurons, and maintain neuron survival post-weaning through a TGFβ-driven microglia-like phenotype.

This study uses phenogenomic analysis to uncover virulence mechanisms and drug resistance in Mycobacterium abscessus by integrating phenotyping, genomics, and computational modeling.

This study shows that bacterial infections in Drosophila increase physical activity through Toll-dependent and Toll-independent mechanisms, with activity levels predicting survival.