Author

E. Modave

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

D. Lambrechts· 3 shared A. A. Pane· 1 shared A. Bertotti· 1 shared A. Bikfalvi· 1 shared A. C. O'Farrell· 1 shared A. Emanuelli· 1 shared A. L. Welm· 1 shared A. Lafferty· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersCancer Biology

D. Lambrechts

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Neuro-immune Crosstalk in the Enteric Nervous System from Early Postnatal Development to Adulthood

M. F. Viola, M. Chavero Pieres, E. Modave, N. Stakenborg, M. Delfini, N. Fabre, I. Appeltans, T. Martens, K. Vandereyken, J. Van Herck, P. Petry, S. Verheijden, S. De Schepper, A. Sifrim, K. KIERDORF, , G. Boeckxstaens

This study shows that intestinal macrophages refine the enteric nervous system early in life by pruning synapses and phagocytosing neurons, and maintain neuron survival post-weaning through a TGFβ-driven microglia-like phenotype.

bioRxiv · May 12, 2022Immunology

CD8+ T Cell Metabolic Rewiring Defined by Single-Cell RNA-Sequencing Identifies a Critical Role of ASNS Expression Dynamics in T Cell Differentiation

J. Fernandez-Garcia, F. Franco, S. Parik, A. A. Pane, D. Broekaert, J. Van Elsen, I. Vermeire, T. Van Brussel, R. Schepers, E. Modave, T. Karakach, P. Carmeliet, D. Lambrechts, P.-C. Ho, S.-M. Fendt

This study uses scRNA-seq to analyze CD8+ T cell metabolic dynamics during activation and differentiation, identifying ASNS expression dynamics as critical for determining T cell fate.

bioRxiv · Jul 27, 2021Immunology

A multi-layered systems approach for renal cell carcinoma

L. Cooley, J. Rudewicz, W. Souleyreau, K. Clarke, F. Falciani, M. Dufies, S. Verbeke, A. Emanuelli, S. Benzekry, C. Taing, E. J. Ribot, S. Miraux, D. Lambrechts, E. Modave, R. Pineau, , A. Bikfalvi

A multi-layered systems approach identifies prognostic and predictive biomarkers for renal cell carcinoma aggressiveness through in vivo models and integrative analysis.

bioRxiv · Jan 13, 2020 · PreprintCancer Biology

Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

X. Y. Woo, J. Giordano, A. Srivastava, Z.-M. Zhao, M. W. Lloyd, R. de Bruijn, Y.-S. Suh, R. Patidar, L. Chen, S. Scherer, M. Bailey, C.-H. Yang, E. Cortes-Sanchez, Y. Xi, J. Wang, , B. E Welm

This study shows that copy number profiles are conserved in patient-derived xenografts (PDXs) through engraftment and passaging, indicating minimal impact from the mouse host on tumor evolution.

bioRxiv · Dec 3, 2019Cancer Biology