Hippo Signaling Pathway Activation during SARS-CoV-2 Infection Contributes to Host Antiviral Response
G. Garcia, Y. Wang, J. I. Irudayam, A. V. Jeyachandran, S. C. Cario, C. Sen, S. Li, Y. Li, A. Kumar, K. Nielsen-Saines, S. W. French, P. S. Shah, K. Morizono, B. Gomperts, A. Deb, , V. Arumugaswami
This study identifies Hippo signaling pathway activation as an antiviral response to SARS-CoV-2 infection and shows pharmacological targeting of the pathway can reduce virus replication.
bioRxiv · Apr 7, 2022Microbiology