Cancer BiologybioRxiv
Dietary suppression of MHC-II expression in intestinal stem cells enhances intestinal tumorigenesis
S. Beyaz, J. Roper, M. E. Xifaras…·O. H. Yilmaz
The paper shows that a high fat diet reduces MHC-II expression in intestinal stem cells, promoting tumorigenesis by altering immune recognition.
DOI 10.1016/j.stem.2021.08.007