Author

E. Elinav

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. A. Kolodziejczyk· 2 shared A. Eisenberg-Lerner· 1 shared A. Erdemir· 1 shared A. Garipcan· 1 shared A. Giannou· 1 shared A. Javitt· 1 shared A. Kacen· 1 shared A. Kucukural· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCancer Biology

A. A. Kolodziejczyk

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Author profile →

5 papers

Recent·Most cited

Ex vivo intestinal permeability assay (X-IPA) for tracking barrier function dynamics

H. Bootz-Maoz, A. Simon, S. Del Mare-Roumani, Y. Bennet, D. Zheng, S. Amidror, E. Elinav, N. Yissachar

The paper introduces an ex vivo intestinal permeability assay (X-IPA) to quantify gut permeability dynamics and shows that specific microbes and metabolites induce rapid, dose-dependent increases in permeability.

bioRxiv · Nov 8, 2022 · PreprintMicrobiology

The proteasome regulator PSME4 drives immune evasion and abrogates anti-tumor immunity in NSCLC

A. Javitt, M. D. Shmueli, M. P. Kramer, A. A. Kolodziejczyk, I. J. Cohen, I. Kamer, K. Litchfield, E. Bab-Dinitz, O. Zadok, V. Neiens, A. Ulman, L. Radomir, H. Wolf-Levy, A. Eisenberg-Lerner, A. Kacen, , Y. Merbl

This paper identifies PSME4 as a proteasome regulator that suppresses anti-tumor immunity in NSCLC by inhibiting immunoproteasome activity and antigen presentation.

bioRxiv · Oct 24, 2021 · PreprintCancer Biology

The spatio-temporal program of liver zonal regeneration

S. Ben-Moshe, T. Veg, R. Manco, S. Dan, A. A. Kolodziejczyk, K. Bahar Halpern, E. Elinav, S. Itzkovitz

This study uses spatially-resolved single-cell RNA sequencing to analyze mouse liver regeneration after acetaminophen intoxication, revealing zonal dynamics and cell-type-specific responses.

bioRxiv · Aug 11, 2021 · PreprintCell Biology

Peripheral sgp130-mediated trans-signaling blockade induces obesity and insulin resistance in mice via PPARα suppression

T. Lanton, O. Levkovitch-Siany, S. Udi, J. Tam, R. Abramovich, S. Perles, E. Williams, J. Rachmilewitz, U. Mor, E. Elinav, D. Schmidt-Arras, A. Rehman, P. Rosenstiel, A. Giannou, S. Huber, , J. H. Axelrod

This study shows that blocking peripheral sgp130-mediated trans-signaling in mice causes obesity and insulin resistance by suppressing PPARα.

bioRxiv · Sep 24, 2020 · PreprintPhysiology

Dietary suppression of MHC-II expression in intestinal stem cells enhances intestinal tumorigenesis

S. Beyaz, J. Roper, M. E. Xifaras, K. E. Bauer-Rowe, I. Ergin, L. Dohnalova, M. Biton, K. Shekar, H. Mou, O. Eskiocak, D. M. Ozata, C. Chung, K. Papciak, M. Almeqdadi, M. Fein, , O. H. Yilmaz

The paper shows that a high fat diet reduces MHC-II expression in intestinal stem cells, promoting tumorigenesis by altering immune recognition.

bioRxiv · Sep 5, 2020Cancer Biology