Author

A. Kucukural

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:clustering· 1

Frequent Co-Authors

D. M. Ozata· 2 shared H. Mou· 2 shared L. Lifshitz· 2 shared M. Garber· 2 shared S. Beyaz· 2 shared A. Derr· 1 shared A. Desai· 1 shared A. Erdemir· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

D. M. Ozata

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Author profile →

4 papers

Recent·Most cited

CRISPR-induced exon skipping of β-catenin reveals tumorigenic mutants driving distinct subtypes of liver cancer

H. Mou, J. Yue, Y. Jin, Z. Wang, Y. Gao, T. Janowitz, H. V. Meyer, A. Kucukural, J. E. Wilkinson, D. M. Ozata, S. Beyaz

This study shows CRISPR/Cas9 can induce exon skipping in β-catenin, creating gain-of-function mutations that drive distinct liver cancer subtypes in mice and are found in human HCC patients.

bioRxiv · Mar 27, 2022Cancer Biology

Dietary suppression of MHC-II expression in intestinal stem cells enhances intestinal tumorigenesis

S. Beyaz, J. Roper, M. E. Xifaras, K. E. Bauer-Rowe, I. Ergin, L. Dohnalova, M. Biton, K. Shekar, H. Mou, O. Eskiocak, D. M. Ozata, C. Chung, K. Papciak, M. Almeqdadi, M. Fein, , O. H. Yilmaz

The paper shows that a high fat diet reduces MHC-II expression in intestinal stem cells, promoting tumorigenesis by altering immune recognition.

bioRxiv · Sep 5, 2020Cancer Biology

Multiple human adipocyte subtypes and mechanisms of their development

S. Y. Min, A. Desai, Z. Yang, A. Sharma, R. M. J. Genga, A. Kucukural, L. Lifshitz, R. Maehr, M. Garber, S. Corvera

The paper identifies four human adipocyte subtypes through single-cell transcriptomics and describes their developmental mechanisms and functional roles.

bioRxiv · Jan 31, 2019 · PreprintPhysiology

HIV-1-induced cytokines deplete homeostatic ILCs and expand TCF7-dependent memory NK cells

Y. Wang, K. Gellatly, S. McCauley, P. Vangala, K. Kim, A. Derr, S. Jaiswal, A. Kucukural, P. McDonel, L. Lifshitz, T. Greenough, J. Houghton, M. Garber, J. Luban

This study shows HIV-1-induced cytokines deplete homeostatic ILCs and drive the expansion of TCF7-dependent memory NK cells.

bioRxiv · Jan 2, 2019 · PreprintImmunology