Cell BiologybioRxivPreprint
PAK1-dependant mechanotransduction enables myofibroblast nuclear adaptation and chromatin organisation during fibrosis
E. Jokl, A. Mullan, K. Simpson…·K. Piper Hanley
The paper identifies PAK1-dependent mechanotransduction as critical for myofibroblast nuclear adaptation and chromatin organization during fibrosis, showing its impact on gene regulation and disease progression.