S. Raza

PCIF1 is partly cytoplasmic, dynamically localizes to stress granules and binds mRNA coding regions upon oxidative stress

This study shows PCIF1 is cytoplasmic, localizes to stress granules, and binds mRNA coding regions during oxidative stress, suggesting a role in RNA surveillance independent of its methyltransferase activity.

Comparative Pore Structure and Dynamics for Bacterial Microcompartment Shell Protein Assemblies in Sheets or Shells

The paper compares pore structure and dynamics in bacterial microcompartment shell proteins under different geometries using molecular modeling and simulations.

Therapeutic targeting of SLC6A8 creatine transporter inhibits KRAS mutant and wildtype colon cancer and modulates human creatine levels

RGX-202 inhibits CRC growth by targeting SLC6A8 creatine transporter, reduces creatine and ATP levels, and shows efficacy in multiple tumor models and human trials.

An assessment of efficacy of Iodine complex (Renessans) against SARS-CoV-2 in non-human primates (Rhesus macaque)

This study evaluates the efficacy of Renessans, an iodine complex, against SARS-CoV-2 in Rhesus macaques, showing reduced viral load and faster clearance in treated groups.

An in vitro assessment of anti-SARS-CoV-2 activity of oral preparations of iodine complexes (RENESSANS)

This study assesses the in vitro anti-SARS-CoV-2 activity of iodine complex oral formulations, finding that higher concentrations show significant inhibition of viral replication and cytopathic effects.

SOX9 is required for kidney fibrosis and regulates NAV3 to control renal myofibroblast function in mice and humans

This study identifies SOX9 as essential for kidney fibrosis and shows it regulates NAV3 to control myofibroblast function in mice and humans.