Lactate activates the mitochondrial electron transport chain independent of its metabolism
X. Cai, C. C. Ng, O. Jones, T. S. Fung, K. Ryu, D. Li, C. B. Thompson
This study shows lactate activates the mitochondrial electron transport chain without being metabolized, suppressing glycolysis and enhancing oxidative phosphorylation in various cell types.
bioRxiv · Aug 2, 2023 · PreprintCell Biology