Author

A. Son

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:protein folding & dynamics· 3 Research Focus:drug response / drug discovery· 2 Organism:E. coli· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. Horowitz· 3 shared T. J. Litberg· 2 shared A. Ledreux· 1 shared B. Sathyamoorthy· 1 shared B. Seong· 1 shared C. M. Donnelly· 1 shared C. Zhang· 1 shared D. Paredes· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiophysics

S. Horowitz

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

G-quadruplexes rescuing protein folding

A. Son, V. Huizar Cabral, T. J. Litberg, S. Horowitz

This study shows G-quadruplexes can accelerate protein folding by rescuing kinetically trapped intermediates in E. coli, improving folding quality rather than just preventing aggregation.

bioRxiv · Sep 9, 2022Biophysics

Why are G-quadruplexes good at preventing protein aggregation?

T. J. Litberg, R. K. R. Sannapureddi, Z. Huang, A. Son, B. Sathyamoorthy, S. Horowitz

This study identifies structural factors that enable G-quadruplexes to prevent protein aggregation, offering insights into their role in disease prevention.

bioRxiv · Aug 23, 2022Biophysics

Foldamers Reveal and Validate Novel Therapeutic Targets Associated with Toxic α-Synuclein Self-Assembly

J. Ahmed, T. C. Fitch, C. M. Donnelly, J. A. Joseph, M. M. Bassil, A. Son, C. Zhang, A. Ledreux, S. Horowitz, Y. Qin, D. Paredes, S. Kumar

This study identifies and validates novel therapeutic targets for Parkinson's disease by analyzing α-Synuclein self-assembly using foldamers and multiple assays.

bioRxiv · May 8, 2021Biochemistry

The SARS-CoV-2 RNA interactome

S. Lee, Y.-s. Lee, Y. Choi, A. Son, Y. Park, K.-M. Lee, J. Kim, J.-S. Kim, V. N. Kim

This study identifies 109 host factors interacting with SARS-CoV-2 RNA and reveals their roles in antiviral or proviral functions through RNP capture and knockdown experiments.

bioRxiv · Nov 2, 2020Microbiology

Conversion of a soluble protein into a potent chaperone in vivo

S. I. Choi, S. B. Kwon, K. Ryu, A. Son, H. Jeong, K.-H. Lim, K.-H. Kim, B. Seong

This study shows a soluble protein can act as a chaperone in vivo, preventing protein aggregation and aiding folding, similar to known chaperones.

bioRxiv · Mar 19, 2018Biochemistry