ImmunologybioRxiv
Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds
E.-C. Wamhoff, L. Ronsard, J. Feldman…·M. Bathe
This study shows DNA origami scaffolds enhance antibody responses to SARS-CoV-2 RBD without inducing immune memory against the scaffold itself, compared to protein-based VLPs.
DOI 10.1038/s41467-024-44869-0