K. Sugihara

A meta-analysis of the gut microbiome in inflammatory bowel disease patients identifies disease-associated small molecules

This study identifies disease-associated small molecules from the gut microbiome of IBD patients using metagenomic analysis and synthetic biology.

Mineral phase analysis of various marine-species shells and skeletons collected in Japan: Implications for marine biominerals

The paper analyzes mineral phases in marine species shells and skeletons using XRD, finding calcite, aragonite, or their mixtures, with MgCO3 content varying taxonomically and environmentally.

Mucolytic bacteria license pathobionts to acquire host-derived nutrients during dietary nutrient restriction

The paper shows that mucolytic bacteria enable pathobionts to acquire host-derived nutrients during dietary restriction, allowing them to thrive in the gut.

Site-specific adaptation mechanisms of an oral pathobiont in the oral and gut mucosae

This study identifies adaptation mechanisms of Klebsiella aerogenes in oral and gut mucosae, revealing distinct gene usage for colonization in each environment.

A new microcirculation culture method with a self-organized capillary network

This paper introduces a microcirculation culture method that creates a self-organized capillary network, enabling perfusion and observation of vascular remodeling and cell behavior.

MUTE Directly Orchestrates Cell State Switch and the Single Symmetric Division to Create Stomata

The paper identifies MUTE's role in orchestrating cell state switch and single symmetric division during stomatal differentiation by regulating gene expression and forming an Incoherent Type 1 Feed-Forward Loop.