Author

K. Weaver

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Organism:rat· 2 Assay:clinical cohort / trial· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

A. M. Mitzey· 2 shared A. M. Weiler· 2 shared A. Mejia· 2 shared A. Possell· 2 shared A. S. Jaeger· 2 shared C. M. Crooks· 2 shared E. A. Brown· 2 shared E. L. Mohr· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. M. Mitzey

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Prior dengue immunity enhances Zika virus infection of the maternal-fetal interface in rhesus macaques

C. M. Crooks, A. M. Weiler, S. L. Rybarczyk, M. I. Bliss, A. S. Jaeger, M. E. Murphy, H. A. Simmons, A. Mejia, M. K. Fritsch, J. M. Hayes, J. C. Eickhoff, A. M. Mitzey, E. Razo, K. M. Braun, E. A. Brown, , M. T. Aliota

This study shows that prior dengue virus immunity enhances Zika virus infection at the maternal-fetal interface in rhesus macaques but does not affect plasma replication or fetal outcomes.

bioRxiv · Jan 25, 2021 · PreprintMicrobiology

African-lineage Zika virus replication dynamics and maternal-fetal interface infection in pregnant rhesus macaques

C. M. Crooks, A. M. Weiler, S. L. Rybarczyk, M. I. Bliss, A. S. Jaeger, M. E. Murphy, H. A. Simmons, A. Mejia, M. K. Fritsch, J. M. Hayes, J. C. Eickhoff, A. M. Mitzey, E. Razo, K. Braun, E. A. Brown, , T. C. Friedrich

This study infects pregnant rhesus macaques with African- and Asian-lineage Zika virus to compare their pathogenesis, finding similar replication kinetics but higher viral burden in maternal-fetal interface tissues with African-lineage isolates.

bioRxiv · Nov 30, 2020Microbiology

Characterization of apo-form selective inhibition of indoleamine 2,3-dioxygenase.

R. F. Ortiz-Meoz, L. Wang, R. Matico, A. Rutkowska, M. De la Rosa, S. Bedard, R. Midgett, K. Strohmer, D. Thomson, C. Zhang, M. Mebrahtu, J. Guss, R. Totoritis, T. Consler, N. Campobasso, , G. Zhang

This study compares two IDO1 inhibitors, showing GSK5628 selectively inhibits apo-IDO1 by competing with heme, while epacadostat binds to the heme cofactor, leading to longer-lasting inhibition.

bioRxiv · May 7, 2020Biochemistry

Complete blood count with differential: An effective diagnostic for IBS subtype in the context of BMI?

J. Robinson, C. Boulineaux, K. Butler, P. Joseph, M. Murray, S. Pocock, L. Sherwin, S. Turkington, K. Weaver, W. Henderson

The paper analyzes CBC-D data from a clinical cohort to identify potential biomarkers for IBS subtypes and BMI, finding significant associations but poor predictive performance.

bioRxiv · Apr 18, 2019 · PreprintImmunology