Author

M. Murray

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Evolutionary Biology· 3 Ecology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 6 Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Assay:whole-genome sequencing· 3 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

M. R. Farhat· 2 shared R. Calderon· 2 shared A. Bates· 1 shared A. Meibom· 1 shared A. Minoda· 1 shared A. Sloutsky· 1 shared B. de Jong· 1 shared C. Boulineaux· 1 shared

Activity by Year

2018-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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2 shared papersEvolutionary Biology

M. R. Farhat

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Author profile →

10 papers

Recent·Most cited

Ancient genomics reveals a genetic continuum with dual structure in the Classic Copan

M. Murray, S. Nakamura, M. Fuentes, M. Ogawa, L. M. Cassidy, T. Gakuhari, S. Nakagome

The paper analyzes ancient genomes from Classic Copan, revealing a genetic continuum with dual ancestral structure between Mesoamerican and South American Farmer ancestry.

bioRxiv · May 17, 2024 · PreprintEvolutionary Biology

ROCK2 Knockout Improves Proliferation Rate in a Cellular Model of Down Syndrome

J. LeBlanc-Straceski, R. Williams, K. Ward, A. Bates, C. Duran, L. Anderson, M. Murray, J. PereiraBadji, C. Shoushani, J. Thibault

ROCK2 knockout improves cell proliferation in a trisomy 21 cellular model of Down Syndrome, with no effect in euploid cells.

bioRxiv · Oct 20, 2022 · PreprintCell Biology

A ten-year community reporting database reveals rising coyote boldness and associated human concern in Edmonton, Canada

J. J. Farr, M. J. Pruden, R. Glover, M. Murray, S. A. Sugden, H. W. Harshaw, C. Cassady St. Clair

The paper analyzes 9,134 community reports of coyote interactions in Edmonton over 10 years, finding increasing coyote boldness and human concern, linked to specific spatial, temporal, and contextual factors.

bioRxiv · Oct 18, 2022Ecology

The mesoglea buffers the physico-chemical microenvironment of photosymbionts in the upside-down jellyfish Cassiopea sp.

N. H. Lyndby, M. Murray, E. Trampe, A. Meibom, M. Kühl

This study investigates how the mesoglea in Cassiopea sp. buffers O2 and pH during light-dark cycles by measuring light, O2, and pH dynamics in living specimens.

bioRxiv · Oct 6, 2022Ecology

Ferroptosis Regulation by the NGLY1/NFE2L1 Pathway

G. C. Forcina, L. Pope, M. Murray, W. Dong, M. Abu-Remaileh, C. R. Bertozzi, S. J. Dixon

This study identifies the NGLY1/NFE2L1 pathway as a regulator of ferroptosis, showing that NGLY1-mediated deglycosylation of NFE2L1 is necessary for its anti-ferroptotic function through GPX4 expression.

bioRxiv · Oct 12, 2021Cell Biology

Complete blood count with differential: An effective diagnostic for IBS subtype in the context of BMI?

J. Robinson, C. Boulineaux, K. Butler, P. Joseph, M. Murray, S. Pocock, L. Sherwin, S. Turkington, K. Weaver, W. Henderson

The paper analyzes CBC-D data from a clinical cohort to identify potential biomarkers for IBS subtypes and BMI, finding significant associations but poor predictive performance.

bioRxiv · Apr 18, 2019 · PreprintImmunology

OVOL2 induces mesenchymal-to-epithelial transition in fibroblasts and enhances reprogramming to epithelial lineages

K. Watanabe, Y. Liu, S. Noguchi, M. Murray, J.-C. Chang, M. Kishima, H. Nishimura, K. Hashimoto, A. Minoda, H. Suzuki

This study identifies OVOL2 as a key factor that induces mesenchymal-to-epithelial transition in fibroblasts and enhances reprogramming to epithelial lineages.

bioRxiv · Mar 14, 2019Cell Biology

Genome wide association with quantitative resistance phenotypes in Mycobacterium tuberculosis reveals novel resistance genes and regulatory regions

M. R. Farhat, L. Freschi, R. Calderon, T. Ioerger, M. Snyder, C. J. Meehan, B. de Jong, L. Rigouts, A. Sloutsky, D. Kaur, S. Sunyaev, D. van Soolingen, J. Shendure, J. Sacchettini, M. Murray

This study identifies novel resistance genes and regulatory regions in Mycobacterium tuberculosis using genome-wide association analysis of drug resistance phenotypes.

bioRxiv · Oct 1, 2018Evolutionary Biology

Rifampicin and rifabutin resistance in 1000 Mycobacterium tuberculosis clinical isolates

M. R. Farhat, J. Sixsmith, R. Calderon, N. Hicks, S. Fortune, M. Murray

The paper investigates rifamycin resistance in Mycobacterium tuberculosis isolates, finding that the D435V rpoB mutation increases IC50 for both rifampicin and rifabutin, suggesting the need to revise RFB testing concentrations.

bioRxiv · Sep 25, 2018Evolutionary Biology

Downregulation of the central noradrenergic system by Toxoplasma gondii infection

I. Alsaady, E. Tedford, M. Alsaad, G. Bristow, S. Kohli, M. Murray, M. Reeves, M. S. Vijayabaskar, S. J. Clapcote, J. Wastling, G. A. McConkey

This study shows that Toxoplasma gondii infection suppresses the noradrenergic system by downregulating DBH, leading to decreased norepinephrine and increased dopamine in infected animals and cells.

bioRxiv · Jun 14, 2018Microbiology