Author

Kate L. Sharp

Philadelphia VA Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:flow cytometry· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

Baofeng HuiD· 3 shared Carla R. ScanzelloiD· 3 shared Kevin G. BurtiD· 3 shared Lance A. MurphyiD· 3 shared Robert L. MauckiD· 3 shared Vu NguyeniD· 3 shared Sung Yeon KimiD· 2 shared Alexander J. KnightsiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersImmunology

Baofeng HuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CD14 plays a critical role in pain and inflammation across multiple models of post-traumatic osteoarthritis

Kevin G. Burt, Sanique M. South, Natalie S. Adamczyk, Vu Nguyen, Shingo Ishihara, Cheng Zhou, Kate L. Sharp, Sung Yeon Kim, Anna E. Rapp, Baofeng Hu, Lance A. Murphy, Hung Li-Yin, De’Broski R. Herbert, Joshua F. Baker, Robert L. Mauck, , Carla R. Scanzello

The study shows CD14 is critical for pain and inflammation in post-traumatic osteoarthritis and that blocking CD14 can reduce pain and mobility loss.

Arthritis & Rheumatology · Mar 8, 2026Peer-reviewedImmunology

Mechano-activation of synovial fibroblasts and macrophages during OA progression in the dynamically stiffening synovial microenvironment

Sung Yeon Kim, Easton C. Farrell, Kevin G. Burt, Bryan Kwok, Qiushi Liang, Alexander J. Knights, Kate L. Sharp, Vu Nguyen, Lance A. Murphy, Baofeng Hu, Alexandra Kahn, Ling Qin, Lin Han B, Tristan Maerz, Rob Mauck, Carla R. Scanzello

This study investigates how synovial microenvironment stiffness changes during OA progression and how it affects fibroblast and macrophage behavior through mechanosignaling and cell-cell interactions.

bioRxiv · Feb 18, 2026 · PreprintBioengineering

CD14-deficiency protects against osteoarthritic subchondral bone sclerosis via enhanced osteoclastogenesis following joint injury

Lance A. Murphy, Kate L. Sharp, Kevin G. Burt, Baofeng Hu, Vu Nguyen, Áurea Rodrigues Borges, Christine B. Chung, Jonathan J. Miner, Robert L. Mauck, Carla R. Scanzello

This study shows CD14-deficiency protects against osteoarthritis-related subchondral bone sclerosis by enhancing osteoclastogenesis post-injury in mice.

bioRxiv · Feb 11, 2026 · PreprintImmunology