Cancer BiologybioRxivPreprint
Non-coding germline GATA3 variants alter chromatin topology and contribute to pathogenesis of acute lymphoblastic leukemia
H. Yang, H. Zhang, Y. Luan…·J. J. Yang
The paper identifies a germline non-coding GATA3 variant that alters chromatin topology and contributes to Ph-like ALL by activating an enhancer and reshaping 3D genome organization.
DOI 10.1101/2020.02.23.961672