Author

D. Kuang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cancer Biology· 2 Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Organism:human· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Organism:non-human primate· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

J. Wang· 4 shared J. Xu· 3 shared Y. Zheng· 3 shared C. Ma· 2 shared D. Wu· 2 shared H. Li· 2 shared H. Liu· 2 shared H. Long· 2 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMicrobiology

J. Wang

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

SCO-pH: Microfluidic dynamic phenotyping platform for high-throughput screening of single cell acidification

H. Jeong, E. A. Leyes Porello, J. G. Rosario, D. Kuang, S. H. Han, J.-Y. Sul, B. Lim, D. Lee, J. Kim

SCO-pH enables high-throughput single-cell acidification analysis by compartmentalizing cells in microfluidic droplets and measuring extracellular pH changes to distinguish metabolic states.

bioRxiv · May 8, 2024Bioengineering

Proteomic Stratification of Prognosis and Treatment Options for Small Cell Lung Cancer

Z. Huo, Y. Duan, D. Zhan, X. Xu, N. Zheng, J. Cai, R. Sun, J. Wang, F. Cheng, Z. Gao, C. Xu, W. Liu, Y. Dong, S. Ma, Q. Zhang, , Y. Wang

This study uses proteomic profiling to stratify small cell lung cancer into three subtypes with distinct clinical outcomes and treatment responses, identifying potential therapeutic targets and improving prognosis prediction.

bioRxiv · Oct 22, 2023 · PreprintCancer Biology

Distinct Single-cell Immune Ecosystems Distinguish True and De Novo HBV-related Hepatocellular Carcinoma Recurrences

S. Chen, C. Huang, G. Liao, H. Sun, Y. Xie, J. Wang, M. He, H. Hu, Z. Dai, X. Ren, X. Zeng, Q. Zeng, G. Zhang, C. Liao, W. Xie, , M. Kuang

This study identifies distinct immune ecosystems in true and de novo HBV-related HCC recurrences using single-cell and bulk RNA-sequencing, revealing differences in T cell phenotypes and immune interactions that may inform immunotherapy strategies.

bioRxiv · Jun 2, 2022Immunology

Susceptibility of tree shrew to SARS-CoV-2 infection

Y. Zhao, J. Wang, D. Kuang, J. Xu, M. Yang, C. Ma, S. Zhao, J. Li, H. Long, K. Ding, J. Gao, J. Liu, H. Wang, H. Li, Y. Yang, , X. Peng

This study investigates tree shrew susceptibility to SARS-CoV-2 infection and finds that they show mild symptoms and low viral replication, suggesting limited susceptibility.

bioRxiv · Apr 30, 2020Microbiology

Comparison of SARS-CoV-2 infections among 3 species of non-human primates

S. Lu, Y. Zhao, W. Yu, Y. Yang, J. Gao, J. Wang, D. Kuang, M. Yang, J. Yang, C. Ma, J. Xu, H. Li, S. Zhao, J. Li, H. Wang, , X. Peng

This study compares SARS-CoV-2 infection outcomes in three non-human primate species, finding that M. mulatta is most susceptible, followed by M. fascicularis and C. jacchus.

bioRxiv · Apr 8, 2020 · PreprintMicrobiology

Non-coding germline GATA3 variants alter chromatin topology and contribute to pathogenesis of acute lymphoblastic leukemia

H. Yang, H. Zhang, Y. Luan, T. Liu, K. G. Roberts, M.-x. Qian, B. Zhang, W. Yang, V. Perez-Andreu, J. Xu, S. Iyyanki, D. Kuang, S. C. Reshmi, J. Gastier-Foster, C. Smith, , J. J. Yang

The paper identifies a germline non-coding GATA3 variant that alters chromatin topology and contributes to Ph-like ALL by activating an enhancer and reshaping 3D genome organization.

bioRxiv · Feb 23, 2020 · PreprintCancer Biology

Saak Transform-Based Machine Learning for Light-Sheet Imaging of Cardiac Trabeculation

Y. Ding, V. Gudapati, R. Lin, Y. Fei, S. Song, C.-C. Chang, K. I. Baek, Z. Wang, M. Roustaei, D. Kuang, C.- C. J. Kuo, T. K. Hsiai

This paper develops a Saak transform-based machine learning framework for efficient segmentation and quantification of cardiac trabeculation in light-sheet images after chemotherapy.

bioRxiv · Oct 4, 2019Bioengineering