Methylation of Dual Specificity Phosphatase 4 Controls Cell Differentiation
H. Su, M. Jiang, C. Senevirathne, S. Aluri, T. Zhang, H. Guo, J. Xavier-Ferrucio, S. Jin, N.-T. Tran, S.-M. Liu, C.-W. Sun, Y. Zhu, Q. Zhao, Y. Chen, L. Cable, , X. Zhao
This study identifies PRMT1-mediated methylation of DUSP4 as a regulator of p38 MAPK activity, influencing megakaryocyte differentiation and thrombocytopenia in myelodysplastic syndromes.
bioRxiv · Dec 16, 2020Cell Biology