Author

L. Dohnalova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

C. A. Thaiss· 3 shared A. C. Wong· 1 shared A. Di Francesco· 1 shared A. Erdemir· 1 shared A. Freund· 1 shared A. G. Deighan· 1 shared A. Garipcan· 1 shared A. Harman· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersMicrobiology

C. A. Thaiss

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Author profile →

3 papers

Recent·Most cited

Interactions between the gut microbiome, dietary restriction, and aging in genetically diverse mice

L. Litichevskiy, M. Considine, J. Gill, V. Shandar, T. O. Cox, H. C. Descamps, K. M. Wright, K. R. Amses, L. Dohnalova, M. J. Liou, M. Tetlak, M. R. Galindo-Fiallos, A. C. Wong, P. Lundgren, J. Kim, , C. A. Thaiss

This study investigates how the gut microbiome interacts with aging and dietary restriction in mice, finding that host genetics significantly influence microbiome features and that dietary restriction does not rejuvenate the microbiome.

bioRxiv · Nov 28, 2023 · PreprintMicrobiology

The microbiota and immune system non-genetically affect offspring phenotypes transgenerationally

J. C. Harris, N. A. Trigg, B. Goshu, Y. Yokoyama, L. Dohnalova, E. K. White, A. Harman, C. A. Thaiss, E. A. Grice, C. C. Conine, T. Kambayashi

The paper shows that microbiota and immune system states can transgenerationally affect offspring phenotypes through epigenetic mechanisms in gametes.

bioRxiv · Apr 6, 2023 · PreprintMicrobiology

Dietary suppression of MHC-II expression in intestinal stem cells enhances intestinal tumorigenesis

S. Beyaz, J. Roper, M. E. Xifaras, K. E. Bauer-Rowe, I. Ergin, L. Dohnalova, M. Biton, K. Shekar, H. Mou, O. Eskiocak, D. M. Ozata, C. Chung, K. Papciak, M. Almeqdadi, M. Fein, , O. H. Yilmaz

The paper shows that a high fat diet reduces MHC-II expression in intestinal stem cells, promoting tumorigenesis by altering immune recognition.

bioRxiv · Sep 5, 2020Cancer Biology