Author

A. Freund

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Animal Behavior & Cognition· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

G. A. Churchill· 2 shared L. Robinson· 2 shared A. Brito· 1 shared A. C. Wong· 1 shared A. Deighan· 1 shared A. Di Francesco· 1 shared A. G. Deighan· 1 shared A. R. Ouellette· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

G. A. Churchill

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Interactions between the gut microbiome, dietary restriction, and aging in genetically diverse mice

L. Litichevskiy, M. Considine, J. Gill, V. Shandar, T. O. Cox, H. C. Descamps, K. M. Wright, K. R. Amses, L. Dohnalova, M. J. Liou, M. Tetlak, M. R. Galindo-Fiallos, A. C. Wong, P. Lundgren, J. Kim, , C. A. Thaiss

This study investigates how the gut microbiome interacts with aging and dietary restriction in mice, finding that host genetics significantly influence microbiome features and that dietary restriction does not rejuvenate the microbiome.

bioRxiv · Nov 28, 2023 · PreprintMicrobiology

Life-long Dietary Restrictions have Negligible or Damaging Effects on Late-life Cognitive Performance: A Key Role for Genetics in Outcomes

A. R. Ouellette, N. Hadad, A. Deighan, L. Robinson, K. M. S. O'Connell, A. Freund, G. A. Churchill, C. Kaczorowski

This study finds that long-term dietary restrictions like caloric restriction or fasting do not improve cognitive performance in genetically diverse mice and may even be harmful, with genetic factors playing a key role in memory outcomes.

bioRxiv · Apr 9, 2022Animal Behavior & Cognition

Pharmacological inhibition of longevity regulator PAPP-A restrains mesenchymal stromal cell activity

M. Mohrin, J. Liu, J. Zavala-Solorio, S. Bhargava, J. M. Trumble, A. Brito, D. Hu, D. Brooks, M. L. Bouxsein, R. Baron, Y. Kutskova, A. Freund

This study shows that inhibiting PAPP-A reduces collagen and ECM gene expression and modulates mesenchymal stromal cell activity in mice.

bioRxiv · Feb 5, 2020 · PreprintPhysiology