Author

L. Edwards

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Blanchard· 1 shared A. Carter· 1 shared A. Fisher· 1 shared A. Greenbaum· 1 shared A. Moatti· 1 shared A. Tata· 1 shared A. Taylor· 1 shared C. Furdui· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCell Biology

A. Blanchard

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Itaconate stabilizes CPT1a to enhance lipid utilization during inflammation

R. Mainali, N. Buechler, C. Ortero, L. Edwards, C.-C. Key, C. Furdui, M. A. Quinn

This study shows itaconate stabilizes CPT1a to enhance lipid utilization during inflammation, revealing a novel metabolic role in modulating fatty acid oxidation during sepsis.

bioRxiv · Aug 14, 2023Physiology

Novel porcine model reveals two distinct LGR5 cell types during lung development and homeostasis

K. Polkoff, R. Lampe, N. K. Gupta, Y. Murphy, J. Chung, A. Carter, J. M. Simon, A. Moatti, P. Kadur Lakshminarasimha Murthy, K. Gleason, L. Edwards, A. Greenbaum, A. Tata, P. R. Tata, J. A. Piedrahita

The paper identifies two distinct LGR5+ cell types in the lung using a novel porcine model, showing conservation in humans but not mice.

bioRxiv · Dec 9, 2022Cell Biology

Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis

D. Guillotin, A. Taylor, M. Plate, P. Mercer, L. Edwards, R. Haggart, G. Miele, R. McAnulty, T. Maher, R. E. Hynds, M. Jamal-Hanjani, R. Marshall, A. Fisher, A. Blanchard, R. Chambers

This study identifies key transcriptional pathways in IPF fibroblastic foci using RNA-seq and bioinformatics, highlighting the TSC2/RHEB axis as a potential therapeutic target for fibrosis.

Thorax · Nov 19, 2020Peer-reviewedCell Biology