Cancer BiologybioRxivPreprint
Activation of ERK by altered RNA splicing in cancer
Y. Zhang, M. A. Siraj, P. Chakraborty…·P. Mukherjee
The paper shows that SMNDC1, an upregulated splicing factor in cancer, promotes tumor growth by enhancing ERK1 kinase activity through altered RNA splicing of exon 4.
DOI 10.1101/2022.08.31.505957