Author

L. Gorvel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Olive· 4 shared C. Cano· 2 shared C. Degos· 2 shared G. Guittard· 2 shared M.-S. Rouviere· 2 shared N. Boucherit· 2 shared S. Fattori· 2 shared A. Anastasio· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersImmunology

D. Olive

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Tertiary lymphoid structures are associated with enhanced macrophage activation, immune checkpoint expression and predict outcome in cervical cancer.

L. Gorvel, M. Panouillot, M.-S. Rouviere, E. Billon, S. Fattori, J. Sonongbua, N. Boucherit, A. Ben Amara, O. Quilichini, S. GRANJEAUD, C. Degos, X. Carcopino, E. Lambaudie, A.-S. Chretien, R. Sabatier, , D. Olive

This study shows that tertiary lymphoid structures in cervical cancer are linked to immune activation and better patient outcomes.

bioRxiv · Aug 17, 2023Immunology

Targeting BTN2A1 enhances Vγ9Vδ2 T cell effector functions and triggers tumor cells pyroptosis

A. C. le Floch, C. Imbert, N. Boucherit, L. Gorvel, S. Fattori, F. Orlanducci, A. Le Roy, L. Archetti, L. Crescence, L. Panicot-Dubois, C. Dubois, N. Vey, A. Briantais, A. Anastasio, C. Cano, , D. Olive

bioRxiv · Jun 15, 2023Cancer Biology

Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors

C. Demerle, L. Gorvel, M. Mello, S. Pastor, C. Degos, A. Zarubica, F. Angelis, F. FIORE, J. Nunes, B. Malissen, L. Greillier, G. Guittard, H. Luche, F. Barlesi, D. Olive

bioRxiv · Nov 4, 2022 · PreprintImmunology

Vγ9Vδ2 T cells are potent inhibitors of SARS-CoV-2 replication and exert effector phenotypes in COVID-19 patients

L. Gay, M.-S. Rouviere, S. Mezouar, M. Richaud, L. Gorvel, E. Foucher, L. Madakamutil, B. La Scola, A. Menard, J. Allardet-Servent, P. Halfon, P. Frohna, C. Cano, J.-L. Mege, D. Olive

This paper investigates how SARS-CoV-2 affects Vγ9Vδ2 T cells in patients and shows that anti-BTN3A activation enhances their antiviral response.

bioRxiv · Apr 15, 2022 · PreprintImmunology