Author

H. Luche

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

A. M. Carmo· 2 shared A. Novoa· 2 shared B. Malissen· 2 shared L. Oliveira· 2 shared M. Mallo· 2 shared M. S. Cardoso· 2 shared R. F. Santos· 2 shared A. De Sousa Linhares· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. M. Carmo

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Deconstructing Complexity: A Computational Topology Approach to Trajectory Inference in the Human Thymus with tviblindi

J. Stuchly, D. Novak, N. Brdickova, P. Hadlova, V. Sadilek, A. Iksi, D. Kuzilkova, M. Svaton, G. A. Saad, P. Engel, H. Luche, A. E. Sousa, A. R. M. Almeida, T. Kalina

This paper introduces tviblindi, a trajectory inference tool for thymus development, revealing new insights into T cell maturation and regulatory T cell subpopulations.

bioRxiv · Jul 13, 2023 · PreprintImmunology

Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors

C. Demerle, L. Gorvel, M. Mello, S. Pastor, C. Degos, A. Zarubica, F. Angelis, F. FIORE, J. Nunes, B. Malissen, L. Greillier, G. Guittard, H. Luche, F. Barlesi, D. Olive

bioRxiv · Nov 4, 2022 · PreprintImmunology

The dual character of the inhibitory functions of CD6

R. F. Santos, A. De Sousa Linhares, M. S. Cardoso, A. Novoa, H. Luche, F. Gartner, B. Malissen, P. Steinberger, S. Davis, M. Mallo, L. Oliveira, A. M. Carmo

This study investigates CD6's dual inhibitory and costimulatory functions, showing it suppresses T cell responsiveness via its cytoplasmic domain and modulates autoimmunity through extracellular interactions.

bioRxiv · Apr 29, 2022 · PreprintImmunology

CD5L constraints acute and systemic inflammation and can be a novel potent therapeutic agent against sepsis

L. Oliveira, A. P. Gomes, R. F. Santos, M. S. Cardoso, A. Novoa, H. Luche, F. Gärtner, B. M. Malissen, M. Mallo, A. M. Carmo

This paper demonstrates that CD5L reduces sepsis severity by both anti-bacterial and anti-inflammatory mechanisms, showing therapeutic potential in mouse models.

bioRxiv · Mar 8, 2022 · PreprintImmunology