S. Mezouar

This paper shows that inhibiting PPT1 with ezurpimtrostat enhances anti-PD-1 immunotherapy in liver cancer by converting cold to hot tumors.

This study shows that live Coxiella burnetii infection reduces membrane-bound E-cadherin and alters the E-cadherin/{beta}-catenin signaling pathway in BeWo cells.

This paper investigates how SARS-CoV-2 affects Vγ9Vδ2 T cells in patients and shows that anti-BTN3A activation enhances their antiviral response.

This study shows that GNS561, an autophagy inhibitor, effectively targets both cancer stem cells and bulk tumor cells in hepatocellular carcinoma and colorectal cancer metastasis.

The paper develops a non-invasive method to detect Enterovirus-specific antibodies in gorilla faeces, finding specific antibodies in 4/16 gorilla samples and 2/3 human samples.

This study shows GNS561, an autophagy inhibitor, has strong antiviral effects against SARS-CoV-2, both alone and in combination with remdesivir.

This paper evaluates GNS561, a PPT1 inhibitor, showing its efficacy against HCC by modulating lysosomal functions and inducing cell death in vitro and in vivo.

This study shows SARS-CoV-2 infects monocytes and macrophages, inducing immunoregulatory cytokine secretion and M2-type transcriptional changes, leading to immunoparalysis in Covid-19 patients.

This study shows that SARS-CoV-2 infection and cytokine production in human monocytes vary with the time of day, suggesting circadian rhythm influences viral progression and immune response.