F. Fiore

The chemopreventive effects of Curcumin against oxidative stress induced by Cadmium or H2O2 are mediated by Nrf2/ARE signaling and protective autophagy in myeloid cells

This study shows that curcumin protects myeloid cells from cadmium and H2O2-induced oxidative stress through Nrf2/ARE signaling and autophagy.

Plasmacytoid dendritic cells are dispensable or detrimental in murine systemic or respiratory viral infections

This study shows that plasmacytoid dendritic cells (pDCs) and their interferons are dispensable or harmful in systemic and respiratory viral infections in mice.

Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors

Cellular selectivity of STING stimulation determines priming of tumor-specific T cell responses

This study shows that targeting STING in dendritic cells with cGAMP-VLP enhances tumor-specific T cell responses and synergizes with PD1 blockade for tumor eradication, while synthetic CDN causes systemic T cell activation without specific T cell differentiation.