J.-L. Mege

This study shows SARS-CoV-2 preferentially infects the apical side of intestinal cell monolayers, causing barrier damage and potential systemic spread.

The paper identifies and characterizes an HtrA sheddase produced by Coxiella burnetii and shows its role in cleaving E-cadherin, inducing M2 polarization, and enhancing bacterial replication.

This study shows that live Coxiella burnetii infection reduces membrane-bound E-cadherin and alters the E-cadherin/{beta}-catenin signaling pathway in BeWo cells.

This paper investigates how SARS-CoV-2 affects Vγ9Vδ2 T cells in patients and shows that anti-BTN3A activation enhances their antiviral response.

This study shows GNS561, an autophagy inhibitor, has strong antiviral effects against SARS-CoV-2, both alone and in combination with remdesivir.

This study shows SARS-CoV-2 infects monocytes and macrophages, inducing immunoregulatory cytokine secretion and M2-type transcriptional changes, leading to immunoparalysis in Covid-19 patients.

This study shows that SARS-CoV-2 infection and cytokine production in human monocytes vary with the time of day, suggesting circadian rhythm influences viral progression and immune response.