Author

L. Harshman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 3 Assay:ChIP-seq· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

N. Ahituv· 3 shared L. Carbone· 2 shared M. Okhovat· 2 shared S. Ward· 2 shared A. A. Hoffmann· 1 shared A. C. Lima· 1 shared A. M. Stendahl· 1 shared A. Sohota· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersEvolutionary Biology

N. Ahituv

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Author profile →

4 papers

Recent·Most cited

TAD Evolutionary and functional characterization reveals diversity in mammalian TAD boundary properties and function

M. Okhovat, J. VanCampen, A. C. Lima, K. Nevonen, C. E. Layman, S. Ward, J. Herrera, A. M. Stendahl, R. Yang, L. Harshman, W. Li, R. R. Sheng, Y. Mao, L. Fedorov, B. Ndjamen, , L. Carbone

The paper analyzes TAD boundaries across species to show evolutionary conservation and functional significance, finding ultraconserved boundaries have stronger insulation and CTCF binding.

bioRxiv · Mar 7, 2023Evolutionary Biology

Lipidomic profiling reveals concerted temporal patterns of functionally related lipids in Aedes aegypti females following blood feeding

M.-J. Lau, S. Nie, Q. Yang, L. Harshman, C. Mao, N. A. Williamson, A. A. Hoffmann

This study identifies temporal lipidomic changes in Aedes aegypti mosquitoes post-blood meal, highlighting functional lipid patterns linked to reproduction.

bioRxiv · May 18, 2022 · PreprintBiochemistry

The cis-regulatory effects of modern human-specific variants

C. V. Weiss, L. Harshman, F. Inoue, H. B. Fraser, D. A. Petrov, N. Ahituv, D. Gokhman

The paper investigates the regulatory effects of modern human-specific variants using a massively parallel reporter assay in three cell types, finding 1,791 active sequences and 407 driving differential expression.

bioRxiv · Oct 7, 2020Evolutionary Biology

Co-option of the lineage-specific LAVA retrotransposon in the gibbon genome

M. Okhovat, K. A. Nevonen, B. Davis, P. Michener, S. Ward, M. Milhaven, L. Harshman, A. Sohota, J. D. Fernandes, S. R. Salama, R. J. O'Neill, N. Ahituv, K. R. Veeramah, L. Carbone

This study investigates the role of the lineage-specific LAVA retrotransposon in gibbon gene regulation, finding it overlaps with enhancer chromatin states and is associated with gene expression and selection.

bioRxiv · Apr 6, 2020Evolutionary Biology