Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
H. P. Nguyen, R. Sheng, E. Murray, Y. Ito, M. Bruck, C. Biellak, K. An, F. Lynce, D. A. Dillon, M. J. M. Magbanua, L. A. Huppert, H. Hammerlindl, L. Esserman, J. M. Rosenbluth, N. Ahituv
The paper shows engineered adipocytes can suppress cancer progression by competing for nutrients in multiple cancer types.
bioRxiv · Mar 28, 2023 · PreprintCancer Biology
M. Okhovat, J. VanCampen, A. C. Lima, K. Nevonen, C. E. Layman, S. Ward, J. Herrera, A. M. Stendahl, R. Yang, L. Harshman, W. Li, R. R. Sheng, Y. Mao, L. Fedorov, B. Ndjamen, , L. Carbone
The paper analyzes TAD boundaries across species to show evolutionary conservation and functional significance, finding ultraconserved boundaries have stronger insulation and CTCF binding.
bioRxiv · Mar 7, 2023Evolutionary Biology
S. Whalen, F. Inoue, H. Ryu, T. Fair, E. Markenscoff-Papadimitriou, K. Keough, M. Kircher, B. Martin, B. Alvarado, O. Elor, D. L. Cintron, A. Williams, M. A. H. Samee, S. Thomas, R. Krencik, , K. S. Pollard
The paper uses machine learning to analyze human-chimpanzee variants in HARs, finding 43% affect chromatin state and 14% affect neurodevelopmental enhancer activity, with species-specific activity predicted by transcription factor footprints.
bioRxiv · Sep 28, 2022Evolutionary Biology
K. D. Koh, L. R. Bonser, W. L. Eckalbar, J. Shen, O. Yizhar-Barnea, X. Zeng, D. I. Sun, L. T. Zlock, W. E. Finkbeiner, N. Ahituv, D. J. Erle
The paper identifies cell type-selective IL-13-responsive enhancers in airway epithelial cells and demonstrates their therapeutic potential for asthma by targeting mucin production.
bioRxiv · Oct 8, 2021 · PreprintImmunology
C. V. Weiss, L. Harshman, F. Inoue, H. B. Fraser, D. A. Petrov, N. Ahituv, D. Gokhman
The paper investigates the regulatory effects of modern human-specific variants using a massively parallel reporter assay in three cell types, finding 1,791 active sequences and 407 driving differential expression.
bioRxiv · Oct 7, 2020Evolutionary Biology
M. Okhovat, K. A. Nevonen, B. Davis, P. Michener, S. Ward, M. Milhaven, L. Harshman, A. Sohota, J. D. Fernandes, S. R. Salama, R. J. O'Neill, N. Ahituv, K. R. Veeramah, L. Carbone
This study investigates the role of the lineage-specific LAVA retrotransposon in gibbon gene regulation, finding it overlaps with enhancer chromatin states and is associated with gene expression and selection.
bioRxiv · Apr 6, 2020Evolutionary Biology