Cell BiologybioRxivPreprint
Inositol pyrophosphate dynamics reveals control of the yeast PHO starvation program through 1,5-IP8 and the SPX domain of Pho81
V. Chabert, G. Kim, D. Qiu…·G. Liu
The paper shows that 1,5-IP8 decline triggers the yeast PHO starvation response by inactivating Pho81 through its SPX domain, revealing a unified model of phosphate signaling across eukaryotes.
DOI 10.1101/2023.02.14.528555