Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
S.-H. Chen, S. Prakash, E. Helgason…·I. E. Wertz
This study shows proteasome-generated peptides from degraded proteins induce cell death by neutralizing IAPs, explaining the efficacy of proteolysis-modulating drugs like thalidomide analogs and bortezomib.
A. A. Anand, L. R. Kenner, H. C. Nguyen…·A. Frost
The paper reports cryoEM structures of eIF2 bound to eIF2B, revealing the mechanism of GDP exchange and phosphoregulation in the integrated stress response.
R. Otten, L. Liu, L. R. Kenner…·J. S. Fraser
This study uses directed evolution to identify mutations that restore catalytic activity in a mutant enzyme, revealing how conformational dynamics are shaped by evolutionary selection.