Pharmacology & ToxicologybioRxiv
Development of Enterovirus anti-viral agents that target the viral 2C protein
R. Kejriwal, T. Evans, J. Calabrese…·S. White
This study develops broad-spectrum anti-viral compounds targeting the conserved EV 2C protein, showing low IC50 values and suggesting a role for 2C in capsid assembly.
DOI 10.1002/cmdc.202200541