Author

L.-W. Guo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:rat· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Wang· 3 shared M. Zhang· 3 shared G. Urabe· 2 shared H. Shen· 2 shared J. Li· 2 shared J. Plutzky· 2 shared K. C. Kent· 2 shared Y. Huang· 2 shared

Activity by Year

2019-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPathology

B. Wang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The BD2 domain of BRD4 is a determinant in EndoMT and vein graft neointima formation

M. Zhang, B. Wang, G. Urabe, Y. Huang, J. Plutzky, K. C. Kent, L.-W. Guo

This study identifies the BD2 domain of BRD4 as critical for EndoMT and vein graft neointima formation, suggesting it as a therapeutic target.

Cellular Signalling · Sep 1, 2019Peer-reviewedPathology

BRD2 regulation of sigma-2 receptor expression upon cytosolic cholesterol deprivation

H. Shen, J. Li, X. Xie, H. Yang, M. Zhang, B. Wang, C. Kent, J. Plutzky, L.-W. Guo

This study shows BRD2 and SREBP2 work together to increase sigma-2 receptor expression when cells lack cytosolic cholesterol.

bioRxiv · Aug 28, 2019Biochemistry

A non-canonical role and regulations of polo-like kinase-4 in fibroblast cell-type transition

J. Li, G. Urabe, M. Zhang, Y. Huang, B. Wang, L. Marcho, H. Shen, K. C. Kent, L.-W. Guo

This study identifies a non-canonical role for PLK4 in fibroblast cell-type transition and shows its regulation by BRD4 and PDGFR pathways, suggesting PLK4 inhibition as a potential anti-fibrotic intervention.

bioRxiv · Mar 31, 2019 · PreprintCell Biology