Cancer BiologybioRxivPreprint
Both CD8 and CD4 T cells contribute to immunosurveillance preventing the development of neoantigen-expressing autochthonous sarcomas
Jonathon E. Himes, Amy J. Wisdom, Laura Wang…·David G. Kirsch
This study develops an autochthonous murine sarcoma model and shows that both CD8 and CD4 T cells are required for immunosurveillance against neoantigen-expressing tumors.
DOI 10.1101/2023.04.04.535550