Pharmacology & ToxicologybioRxiv
Depressive-like behaviors induced by somatostatin-positive GABA neuron silencing are rescued by alpha 5 GABA-A receptor potentiation
C. Fee, T. D. Prevot, K. A. Misquitta…·E. Sibille
This paper shows that silencing somatostatin-positive GABA neurons in mice induces depressive-like behaviors, which are reversed by a 5-GABA-A receptor positive allosteric modulator.
DOI 10.1093/ijnp/pyab002