Cell BiologyCell Stem CellPeer-reviewed
Autophagy counters inflammation-driven glycolytic impairment in aging hematopoietic stem cells
P. V. Dellorusso, M. A. Proven, F. J. Calero-Nieto…·E. Passegue
This study shows autophagy compensates for inflammation-induced metabolic issues in old HSCs, and temporarily boosting autophagy can restore their function.
DOI 10.1016/j.stem.2024.04.020