ImmunologybioRxiv
Pre-existing SIV infection increases expression of T cell markers associated with activation during early Mycobacterium tuberculosis co-infection and impairs TNF responses in granulomas
E. Larson, A. L. Ellis, M. A. Rodgers…·C. A. Scanga
This study shows that pre-existing SIV infection alters T cell phenotypes and reduces TNF responses during early Mtb co-infection, impairing immune control.
DOI 10.4049/jimmunol.2100073