Author

M. Buckley

Centre for Environment, Fisheries and Aquaculture Science

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1 Molecular Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2

Frequent Co-Authors

A. E. Loiselle· 2 shared A. Johnson· 1 shared A. Korcari· 1 shared A. Loiselle· 1 shared A. Reynolds· 1 shared A. van Wijnen· 1 shared C. Mayhew· 1 shared C. P. Miller· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersCell Biology

A. E. Loiselle

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Author profile →

6 papers

Recent·Most cited

Long Amplicon Nanopore Sequencing for Dual-Typing RdRp and VP1 Genes of Norovirus Genogroups I and II in Wastewater

G. Scott, David Ryder, M. Buckley, R. Hill, Samantha Treagus, Tina A. Stapleton, David I. Walker, James A. Lowther, Frederico M. Batista

This paper develops a long amplicon nanopore sequencing method for dual-typing RdRp and VP1 genes of norovirus in wastewater, revealing diverse genotypes and potential for improved epidemiological tracking.

bioRxiv · Mar 27, 2024 · PreprintMolecular Biology

Pioneer transcription factors coordinate active and repressive gene expression states to regulate cell fate

S. Matsui, M. Granitto, M. Buckley, J. Shiley, W. Zacharias, C. Mayhew, H.-W. Lim, M. Iwafuchi

This study shows pioneer transcription factors coordinate with PRDM TFs to repress alternative lineage programs and regulate cell fate.

bioRxiv · Dec 29, 2022 · PreprintCell Biology

Inducible depletion of Scleraxis-lineage cells during tendon healing impairs multi-scale restoration of tendon structure

A. Korcari, S. Muscat, M. Buckley, A. E. Loiselle

This study shows that depletion of Scleraxis-lineage cells during tendon healing impairs early structural and functional recovery but not long-term tendon mechanics.

bioRxiv · Mar 17, 2022 · PreprintCell Biology

Altered TGFB1 regulated pathways promote accelerated tendon healing in the superhealer MRL/MpJ mouse

J. Kallenbach, M. Freeberg, D. Abplanalp, J. Lillis, J. Ashton, A. E. Loiselle, M. Buckley, A. van Wijnen, H. A. Awad

The study compares tendon healing in MRL/MpJ and C57Bl/6J mice, finding altered TGFB1 pathways in MRL mice that reduce fibrosis and promote faster healing.

bioRxiv · Feb 8, 2021Cell Biology

Cryptic Promoter Activation Drives POU5F1 (OCT4) Expression in Renal Cell Carcinoma

K. T. Siebenthall, C. P. Miller, J. D. Vierstra, J. Mathieu, M. Tretiakova, A. Reynolds, R. Sandstrom, E. Rynes, S. J. Neph, E. Haugen, A. Johnson, J. Nelson, D. Bates, M. Diegel, D. Dunn, , S. Akilesh

The paper identifies a HIF-pathway-responsive cryptic promoter driving POU5F1 expression in RCC, linked to poor patient outcomes.

bioRxiv · Jul 27, 2018Cancer Biology

Obesity/Type II Diabetes Promotes Function-Limiting Changes In Flexor Tendon Extracellular Matrix Organization That Are Not Reversed By Restoring Normal Metabolic Function

V. Studentsova, K. Mora, M. Glasner, M. Buckley, A. Loiselle

This study develops a murine model of diabetic tendinopathy and shows that restoring normal metabolic function does not reverse tendon impairments caused by obesity/T2DM.

bioRxiv · Dec 12, 2017Pathology