Author

M. Colombi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Genomics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

M. N. Hall· 4 shared D. Weissenberger· 2 shared E. Dazert· 2 shared L. M. Terracciano· 2 shared M. Coto-Llerena· 2 shared S. Piscuoglio· 2 shared A. Schmidt· 1 shared A. Suslov· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersCancer Biology

M. N. Hall

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Author profile →

4 papers

Recent·Most cited

Elevated arginine levels in liver tumors promote metabolic reprogramming and tumor growth

D. Mossmann, S. Park, B. Ryback, D. Weissenberger, M. Colombi, S. K. Hindupur, E. Dazert, M. Coto-Llerena, E. Caner, V. J. Cenzano, S. Piscuoglio, F. Bosch, L. M. Terracciano, U. Sauer, M. N. Hall

The paper shows elevated arginine levels in liver tumors drive metabolic reprogramming and tumor growth through feedback loops involving ASNS and arginase 1.

bioRxiv · Apr 26, 2022 · PreprintCancer Biology

Adipose mTORC2 is essential for arborization of sensory neurons in white adipose tissue and whole-body energy homeostasis

I. C. Frei, D. Weissenberger, D. Ritz, W. Heusermann, M. Colombi, M. Shimobayashi, M. N. Hall

The paper identifies adipose mTORC2's role in sensory neuron arborization in white adipose tissue and links it to systemic insulin resistance.

bioRxiv · Mar 21, 2022 · PreprintPhysiology

Proteogenomic characterization of hepatocellular carcinoma

C. K. Ng, E. Dazert, T. Boldanova, M. Coto-Llerena, S. Nuciforo, C. Ercan, A. Suslov, M.-A. Meier, T. Bock, A. Schmidt, S. Ketterer, X. Wang, S. Wieland, M. S. Matter, M. Colombi, , M. H. Heim

This study identifies differentially regulated pathways and candidate driver genes in hepatocellular carcinomas through proteogenomic analysis across clinical stages and etiologies.

bioRxiv · Mar 5, 2021 · PreprintGenomics

mTOR dependent transformed human cells have a distinct set of essential genes from bcr-abl transformed cells

M. N. Hall, D. Benjamin, M. Colombi, C. Moroni

The paper identifies essential genes for mTOR-dependent cancer growth that are not essential for bcr-abl transformed cells, suggesting distinct therapeutic targets.

bioRxiv · Aug 16, 2019 · PreprintCell Biology