Anchorage-independent cell proliferation promoted by fascin's F-actin bundling
T. Isogai, V. S. Murali, F. Zhou, X. Wang, D. Rajendran, L. P. Castro, N. Venkateswaran, M. Conacci-Sorrell, G. Danuser
This study identifies fascin-1's role in promoting anchorage-independent proliferation through a novel signaling complex called PASS, which drives Rac1/PAK/JNK signaling in cancer cells.
bioRxiv · May 4, 2024 · PreprintCell Biology