M. Cooke

The roles of GpsB and DivIVA in Staphylococcus aureus growth and division

This study investigates the roles of DivIVA and GpsB in S. aureus cell cycle and morphogenesis, finding that GpsB regulates cell shape by affecting peptidoglycan synthesis.

Towards a General Approach for Bat Echolocation Detection and Classification

This paper introduces BatDetect2, a deep learning pipeline for detecting and classifying bat echolocation calls, showing improved performance across diverse regions and species.

Protein kinase C alpha is a central node for tumorigenic transcriptional networks in human prostate cancer

This study identifies PKC as a key driver of tumorigenic transcriptional networks in prostate cancer by showing its role in cell cycle, EMT, and immune checkpoint regulation.

Mechanisms of protein kinase C epsilon down-regulation by transforming growth factor-beta in lung cancer cells

This study investigates how TGF-beta induces down-regulation of PKCε in lung cancer cells through proteasomal and endolysosomal pathways, independent of transcription and autophagy.

Requirement for PKC epsilon in KRAS-driven lung tumorigenesis

This study shows PKCε is required for KRAS-driven lung tumorigenesis and identifies it as a potential therapeutic target.

Secondary Osteons Scale Allometrically In Mammalian Humerus And Femur

The paper measures secondary osteon dimensions in mammalian bones and finds they scale negatively with body mass, suggesting trade-offs between fracture resistance and osteocyte viability.