Redox regulation of PTPN22 affects the severity of T cell dependent autoimmune inflammation
J. James, Y. Chen, C. Hernandez, F. Forster, M. Dagnell, Q. Cheng, A. A. Saei, H. Gharibi, G. F. Lahore, A. Astrand, R. Malhotra, B. Malissen, R. A. Zubarev, E. Arner, R. Holmdahl
This study shows that redox regulation of PTPN22 via cysteine 129 affects T cell-dependent autoimmune inflammation severity in mice.
bioRxiv · Dec 2, 2021 · PreprintImmunology