Author

E. Arner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

B. Kaczkowski· 3 shared A. T.-J. Kwon· 2 shared M. Takahashi· 2 shared A. A. Saei· 1 shared A. Astrand· 1 shared A. Hasegawa· 1 shared A. Maeda· 1 shared A. Mardinoglu· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersBioengineering

B. Kaczkowski

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Molecular profiling of high-level athlete skeletal muscle after acute exercise - a systems biology approach

S. M. Reitzner, E. B. Emanuelsson, M. Arif, B. Kaczkowski, A. T.-J. Kwon, A. Mardinoglu, E. Arner, M. A. Chapman, C. J. Sundberg

This study examines how acute exercise affects multi-omics profiles in skeletal muscle of trained and untrained individuals, revealing distinct metabolic and transcriptional responses based on training history and exercise type.

bioRxiv · Apr 11, 2023Physiology

Redox regulation of PTPN22 affects the severity of T cell dependent autoimmune inflammation

J. James, Y. Chen, C. Hernandez, F. Forster, M. Dagnell, Q. Cheng, A. A. Saei, H. Gharibi, G. F. Lahore, A. Astrand, R. Malhotra, B. Malissen, R. A. Zubarev, E. Arner, R. Holmdahl

This study shows that redox regulation of PTPN22 via cysteine 129 affects T cell-dependent autoimmune inflammation severity in mice.

bioRxiv · Dec 2, 2021 · PreprintImmunology

Efficient Development of Platform Cell Lines Using CRISPR-Cas9 and Transcriptomics Analysis

A. T.-J. Kwon, K. Mohri, S. Takizawa, T. Arakawa, M. Takahashi, B. Kaczkowski, M. Furuno, H. Suzuki, S. Tagami, H. Mukai, E. Arner

The paper develops CRISPR-Cas9 mutants of U87MG cells to create platform cell lines for drug testing, finding that transcriptomic analysis helps identify clones with minimal phenotypic divergence from wild type.

bioRxiv · Sep 16, 2020 · PreprintBioengineering

Inducing Human Retinal Pigment Epithelium-like Cells from Somatic Tissue

I. N. Woogeng, I. Abugessaisa, A. Tachibana, Y. Sahara, C.-C. Hon, A. Hasegawa, B. Kaczkowski, N. Sakai, M. Nishida, H. Hu, H. Sanyal, J. Sho, T. Kasukawa, M. Takasato, P. Carninci, , C. Kime

This study develops a simplified method to induce RPE-like cells from human fibroblasts and validates their properties using single-cell RNA sequencing.

bioRxiv · Jul 27, 2020Bioengineering