HDAC6 inhibitor ACY-1083 shows lung epithelial protective features in COPD
J. Horndahl, R. Svärd, P. Berntsson, C. Wingren, J. Li, S. M. Abdillahi, B. Ghosh, E. Capodanno, J. Chan, L. Ripa, A. Astrand, V. K. Sidhaye, M. Collins
This study shows that HDAC6 inhibitor ACY-1083 protects lung epithelial function in COPD by reducing permeability and cytokine production under various challenges.
bioRxiv · Mar 21, 2022Cell Biology