M. E. Hughes

This study identifies a distinct pattern of skeletal muscle dysfunction in a mouse model of long-term post-viral lung disease caused by Sendai virus, showing reduced myofiber size without changes in myofiber type or protein synthesis/degradation markers.

This study identifies genomic reversion and increased DNA end resection as mechanisms of resistance to PARP inhibitors and platinum in BRCA1/2-mutant metastatic breast cancer, with RAD51 foci as a potential biomarker.